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Atractylenolide I

Atractylenolide I

Catalog Number: CC8447 Rank: comment rank 5

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Description:

Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.

Chemical Information:

Molecular Weight (MW) 230.30
Formula

 

C15H18O2

 

CAS No. 73069-13-3
Solubility (25°C) * DMSO 46 mg/mL warmed (199.73 mM)
Water Insoluble
Alcohol 46 mg/mL warmed (199.73 mM)


Biological Activity:

Targets
IC50
COX DNA polymerases Quinone reducta IKK β DNA polymerases LOX
15 μM 5 μM 35-50 nM 1 μM 3.3 μM 3.7 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 4.3422 mL 21.7108 mL 43.4216 mL
5 mM 0.8684 mL 4.3422 mL 8.6843 mL
10 mM 0.4342 mL 2.1711 mL 4.3422 mL
50 mM 0.0868 mL 0.4342 mL 0.8684 mL


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