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Description:
Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).
Chemical Information:
Molecular Weight (MW) 435.88 Formula
C19H18ClN3O5S
CAS No. 366789-02-8 Solubility (25°C) * DMSO 87 mg/mL (199.59 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.2942 mL 11.4710 mL 22.9421 mL 5 mM 0.4588 mL 2.2942 mL 4.5884 mL 10 mM 0.2294 mL 1.1471 mL 2.2942 mL 50 mM 0.0459 mL 0.2294 mL 0.4588 mL
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