Description：

Ridaforolimus (Deforolimus, MK-8669) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.

Chemical Information：

Molecular Weight (MW)		990.21
Formula		C53H84NO14P
CAS No.		572924-54-0
Solubility (25°C) *	DMSO	198 mg/mL (199.95 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.0099 mL	5.0494 mL	10.0989 mL
5 mM	0.2020 mL	1.0099 mL	2.0198 mL
10 mM	0.1010 mL	0.5049 mL	1.0099 mL
50 mM	0.0202 mL	0.1010 mL	0.2020 mL

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