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Description:
Retigabine(free base) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.
Chemical Information:
Molecular Weight (MW) 303.33 Formula
C16H18FN3O2
CAS No. 150812-12-7 Solubility (25°C) * DMSO 60 mg/mL (197.8 mM) Water Insoluble Alcohol 35 mg/mL (115.38 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.2967 mL 16.4837 mL 32.9674 mL 5 mM 0.6593 mL 3.2967 mL 6.5935 mL 10 mM 0.3297 mL 1.6484 mL 3.2967 mL 50 mM 0.0659 mL 0.3297 mL 0.6593 mL
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