Description：

Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively.

Chemical Information：

Molecular Weight (MW)		482.82
Formula		C21H15ClF4N4O3
CAS No.		755037-03-7
Solubility (25°C) *	DMSO	97 mg/mL (200.9 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0712 mL	10.3558 mL	20.7117 mL
5 mM	0.4142 mL	2.0712 mL	4.1423 mL
10 mM	0.2071 mL	1.0356 mL	2.0712 mL
50 mM	0.0414 mL	0.2071 mL	0.4142 mL

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