Description：

Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.

Chemical Information：

Molecular Weight (MW)		572.34
Formula		C19H20F3IN2O5S
CAS No.		923032-37-5
Solubility (25°C) *	DMSO	100 mg/mL (174.72 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (174.72 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7472 mL	8.7361 mL	17.4721 mL
5 mM	0.3494 mL	1.7472 mL	3.4944 mL
10 mM	0.1747 mL	0.8736 mL	1.7472 mL
50 mM	0.0349 mL	0.1747 mL	0.3494 mL

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