Description：

A922500 is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferases, hERG, and a panel of anti-targets.

Chemical Information：

Molecular Weight (MW)		428.48
Formula		C26H24N2O4
CAS No.		959122-11-3
Solubility (25°C) *	DMSO	86 mg/mL (200.7 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

c-Kit v-Abl PDGFR 100 nM 600 nM 100 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3338 mL	11.6692 mL	23.3383 mL
5 mM	0.4668 mL	2.3338 mL	4.6677 mL
10 mM	0.2334 mL	1.1669 mL	2.3338 mL
50 mM	0.0467 mL	0.2334 mL	0.4668 mL

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