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Rebastinib (DCC-2036)

Rebastinib (DCC-2036)

Catalog Number: CC2790 Rank: comment rank 5

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$ 224.00
$ 679.00
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Description:

Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1.

Chemical Information:

Molecular Weight (MW) 553.59
Formula

 

C30H28FN7O3

 

CAS No. 1020172-07-9
Solubility (25°C) * DMSO 111 mg/mL (200.5 mM)
Water Insoluble
Alcohol 16 mg/mL (28.9 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8064 mL 9.0320 mL 18.0639 mL
5 mM 0.3613 mL 1.8064 mL 3.6128 mL
10 mM 0.1806 mL 0.9032 mL 1.8064 mL
50 mM 0.0361 mL 0.1806 mL 0.3613 mL


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