Description：

R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.

Chemical Information：

Molecular Weight (MW)		624.42
Formula		C23H24FN6O9P.2Na
CAS No.		1025687-58-4
Solubility (25°C) *	DMSO	6 mg/mL warmed (9.6 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6015 mL	8.0074 mL	16.0149 mL
5 mM	0.3203 mL	1.6015 mL	3.2030 mL
10 mM	0.1601 mL	0.8007 mL	1.6015 mL
50 mM	0.0320 mL	0.1601 mL	0.3203 mL

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