Description：

R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with K_i of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.

Chemical Information：

Molecular Weight (MW)		441.45
Formula		C18H21F2N5O4S
CAS No.		741713-40-6
Solubility (25°C) *	DMSO	60 mg/mL (135.91 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2653 mL	11.3263 mL	22.6526 mL
5 mM	0.4531 mL	2.2653 mL	4.5305 mL
10 mM	0.2265 mL	1.1326 mL	2.2653 mL
50 mM	0.0453 mL	0.2265 mL	0.4531 mL

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