Description：

R406 is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 1.

Chemical Information：

Molecular Weight (MW)		628.63
Formula		C22H23FN6O5.C6H6O3S
CAS No.		841290-81-1
Solubility (25°C) *	DMSO	100 mg/mL (159.07 mM)
	Water	Insoluble
	Alcohol	0 mg/mL (0.0 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5908 mL	7.9538 mL	15.9076 mL
5 mM	0.3182 mL	1.5908 mL	3.1815 mL
10 mM	0.1591 mL	0.7954 mL	1.5908 mL
50 mM	0.0318 mL	0.1591 mL	0.3182 mL

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