Description：

PX-478 2HCl is an orally active, and selective hypoxia-inducible factor-1α (HIF-1α) inhibitor. Phase 1.

Chemical Information：

Molecular Weight (MW)		394.12
Formula		C13H20Cl4N2O3
CAS No.		685898-44-6
Solubility (25°C) *	DMSO	78 mg/mL (197.9 mM)
	Water	78 mg/mL (197.9 mM)
	Alcohol	78 mg/mL (197.9 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5373 mL	12.6865 mL	25.3730 mL
5 mM	0.5075 mL	2.5373 mL	5.0746 mL
10 mM	0.2537 mL	1.2686 mL	2.5373 mL
50 mM	0.0507 mL	0.2537 mL	0.5075 mL

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