Description：

Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.

Chemical Information：

Molecular Weight (MW)		520.62
Formula		C31H32N6O2
CAS No.		483367-10-8
Solubility (25°C) *	DMSO	4 mg/mL warmed (7.68 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9208 mL	9.6039 mL	19.2079 mL
5 mM	0.3842 mL	1.9208 mL	3.8416 mL
10 mM	0.1921 mL	0.9604 mL	1.9208 mL
50 mM	0.0384 mL	0.1921 mL	0.3842 mL

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