Description：

PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.

Chemical Information：

Molecular Weight (MW)		517.96
Formula		C19H17ClFN5S.C4H4O4
CAS No.		866206-55-5
Solubility (25°C) *	DMSO	104 mg/mL (200.78 mM)
	Water	104 mg/mL (200.78 mM)
	Alcohol	98 mg/mL (189.2 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9307 mL	9.6533 mL	19.3065 mL
5 mM	0.3861 mL	1.9307 mL	3.8613 mL
10 mM	0.1931 mL	0.9653 mL	1.9307 mL
50 mM	0.0386 mL	0.1931 mL	0.3861 mL

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