Description：

Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay.

Chemical Information：

Molecular Weight (MW)		438.31
Formula		C18H19N7O2.2ClH
CAS No.		1234015-54-3
Solubility (25°C) *	DMSO	2 mg/mL (4.56 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2815 mL	11.4075 mL	22.8149 mL
5 mM	0.4563 mL	2.2815 mL	4.5630 mL
10 mM	0.2281 mL	1.1407 mL	2.2815 mL
50 mM	0.0456 mL	0.2281 mL	0.4563 mL

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