Description：

A66 is a potent and specific p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity for p110α over other class-I PI3K isoforms.

Chemical Information：

Molecular Weight (MW)		393.53
Formula		C17H23N5O2S2
CAS No.		1166227-08-2
Solubility (25°C) *	DMSO	79 mg/mL (200.74 mM)
	Water	Insoluble
	Alcohol	1 mg/mL (2.54 mM)

Biological Activity：

Targets IC50

Tyr1173 (NR6W ce Tyr992 (NR6W ce Tyr1173 (NR6wtE Tyr992 (NR6wtEG 26 nM 57 nM 37 nM 37nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5411 mL	12.7055 mL	25.4110 mL
5 mM	0.5082 mL	2.5411 mL	5.0822 mL
10 mM	0.2541 mL	1.2706 mL	2.5411 mL
50 mM	0.0508 mL	0.2541 mL	0.5082 mL

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