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Description:
PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM in cell-free assays, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.
Chemical Information:
Molecular Weight (MW) 301.77 Formula
C15H16ClN5
CAS No. 172889-27-9 Solubility (25°C) * DMSO 60 mg/mL (198.82 mM) Water Insoluble Alcohol 2 mg/mL (6.62 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.3138 mL 16.5689 mL 33.1378 mL 5 mM 0.6628 mL 3.3138 mL 6.6276 mL 10 mM 0.3314 mL 1.6569 mL 3.3138 mL 50 mM 0.0663 mL 0.3314 mL 0.6628 mL
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