Description：

AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.

Chemical Information：

Molecular Weight (MW)		313.78
Formula		C17H16ClN3O
CAS No.		1056901-62-2
Solubility (25°C) *	DMSO	62 mg/mL (197.59 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

AChE 0.35 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1869 mL	15.9347 mL	31.8695 mL
5 mM	0.6374 mL	3.1869 mL	6.3739 mL
10 mM	0.3187 mL	1.5935 mL	3.1869 mL
50 mM	0.0637 mL	0.3187 mL	0.6374 mL

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