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Plinabulin (NPI-2358)

Plinabulin (NPI-2358)

Catalog Number: CC1332 Rank: comment rank 5

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Description:

Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 336.39
Formula

 

C19H20N4O2

 

CAS No. 714272-27-2
Solubility (25°C) * DMSO 54 mg/mL warmed (160.52 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.9727 mL 14.8637 mL 29.7274 mL
5 mM 0.5945 mL 2.9727 mL 5.9455 mL
10 mM 0.2973 mL 1.4864 mL 2.9727 mL
50 mM 0.0595 mL 0.2973 mL 0.5945 mL


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