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Description:
Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.
Chemical Information:
Molecular Weight (MW) 336.39 Formula
C19H20N4O2
CAS No. 714272-27-2 Solubility (25°C) * DMSO 54 mg/mL warmed (160.52 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.9727 mL 14.8637 mL 29.7274 mL 5 mM 0.5945 mL 2.9727 mL 5.9455 mL 10 mM 0.2973 mL 1.4864 mL 2.9727 mL 50 mM 0.0595 mL 0.2973 mL 0.5945 mL
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