Description：

PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3Kα mutants E545K and H1047R.

Chemical Information：

Molecular Weight (MW)		570.65
Formula		C29H34N10O3
CAS No.		1173204-81-3
Solubility (25°C) *	DMSO	0.4 mg/mL (0.7 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7524 mL	8.7619 mL	17.5239 mL
5 mM	0.3505 mL	1.7524 mL	3.5048 mL
10 mM	0.1752 mL	0.8762 mL	1.7524 mL
50 mM	0.0350 mL	0.1752 mL	0.3505 mL

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