Description：

Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1; also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.

Chemical Information：

Molecular Weight (MW)		317.34
Formula		C17H19NO5
CAS No.		20069-09-4
Solubility (25°C) *	DMSO	16 mg/mL warmed (50.41 mM)
	Water	Insoluble
	Alcohol	6 mg/mL warmed (18.9 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1512 mL	15.7560 mL	31.5119 mL
5 mM	0.6302 mL	3.1512 mL	6.3024 mL
10 mM	0.3151 mL	1.5756 mL	3.1512 mL
50 mM	0.0630 mL	0.3151 mL	0.6302 mL

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