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Description:
Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.
Chemical Information:
Molecular Weight (MW) 541.02 Formula
C25H25ClN6O4S
CAS No. 934526-89-3 Solubility (25°C) * DMSO 100 mg/mL warmed (184.83 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.8484 mL 9.2418 mL 18.4836 mL 5 mM 0.3697 mL 1.8484 mL 3.6967 mL 10 mM 0.1848 mL 0.9242 mL 1.8484 mL 50 mM 0.0370 mL 0.1848 mL 0.3697 mL
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