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PIK-75 HCl

PIK-75 HCl

Catalog Number: CC1361 Rank: comment rank 5

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Description:

PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.

Chemical Information:

Molecular Weight (MW) 488.74
Formula

 

C16H14BrN5O4S.HCl

 

CAS No. 372196-77-5
Solubility (25°C) * DMSO 4 mg/mL warmed (8.18 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0461 mL 10.2304 mL 20.4608 mL
5 mM 0.4092 mL 2.0461 mL 4.0922 mL
10 mM 0.2046 mL 1.0230 mL 2.0461 mL
50 mM 0.0409 mL 0.2046 mL 0.4092 mL


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