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Pictilisib (GDC-0941)

Pictilisib (GDC-0941)

Catalog Number: CC1221 Rank: comment rank 5

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Description:

Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Phase 2.

Chemical Information:

Molecular Weight (MW) 513.64
Formula

 

C23H27N7O3S2

 

CAS No. 957054-30-7
Solubility (25°C) * DMSO 44 mg/mL (85.66 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9469 mL 9.7344 mL 19.4689 mL
5 mM 0.3894 mL 1.9469 mL 3.8938 mL
10 mM 0.1947 mL 0.9734 mL 1.9469 mL
50 mM 0.0389 mL 0.1947 mL 0.3894 mL


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