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Description:
Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Phase 2.
Chemical Information:
Molecular Weight (MW) 513.64 Formula
C23H27N7O3S2
CAS No. 957054-30-7 Solubility (25°C) * DMSO 44 mg/mL (85.66 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9469 mL 9.7344 mL 19.4689 mL 5 mM 0.3894 mL 1.9469 mL 3.8938 mL 10 mM 0.1947 mL 0.9734 mL 1.9469 mL 50 mM 0.0389 mL 0.1947 mL 0.3894 mL
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