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Description:
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. Phase 1.
Chemical Information:
Molecular Weight (MW) 361.48 Formula
C19H31N5O2
CAS No. 718630-59-2 Solubility (25°C) * DMSO 72 mg/mL(199.18 mM) Water Insoluble Alcohol 72 mg/mL (199.18 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.7664 mL 13.8320 mL 27.6640 mL 5 mM 0.5533 mL 2.7664 mL 5.5328 mL 10 mM 0.2766 mL 1.3832 mL 2.7664 mL 50 mM 0.0553 mL 0.2766 mL 0.5533 mL
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