Description：

PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.

Chemical Information：

Molecular Weight (MW)		501.62
Formula		C28H35N7O2
CAS No.		398493-79-3
Solubility (25°C) *	DMSO	100 mg/mL (199.35 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9935 mL	9.9677 mL	19.9354 mL
5 mM	0.3987 mL	1.9935 mL	3.9871 mL
10 mM	0.1994 mL	0.9968 mL	1.9935 mL
50 mM	0.0399 mL	0.1994 mL	0.3987 mL

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