Description：

PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM in a cell-free assay; 4-fold more selective versus p38β and does not inhibit JNK2. Phase 2.

Chemical Information：

Molecular Weight (MW)		477.3
Formula		C22H19BrF2N2O3
CAS No.		586379-66-0
Solubility (25°C) *	DMSO	96 mg/mL (201.13 mM)
	Water	Insoluble
	Alcohol	7 mg/mL (14.66 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0951 mL	10.4756 mL	20.9512 mL
5 mM	0.4190 mL	2.0951 mL	4.1902 mL
10 mM	0.2095 mL	1.0476 mL	2.0951 mL
50 mM	0.0419 mL	0.2095 mL	0.4190 mL

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