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Description:
PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β.
Chemical Information:
Molecular Weight (MW) 491.49 Formula
C22H20F3N5O3S
CAS No. 869288-64-2 Solubility (25°C) * DMSO 26 mg/mL (52.9 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.0346 mL 10.1731 mL 20.3463 mL 5 mM 0.4069 mL 2.0346 mL 4.0693 mL 10 mM 0.2035 mL 1.0173 mL 2.0346 mL 50 mM 0.0407 mL 0.2035 mL 0.4069 mL
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