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PF-573228

PF-573228

Catalog Number: CC2169 Rank: comment rank 5

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$ 102.00
$ 399.00
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Description:

PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β.

Chemical Information:

Molecular Weight (MW) 491.49
Formula

 

C22H20F3N5O3S

 

CAS No. 869288-64-2
Solubility (25°C) * DMSO 26 mg/mL (52.9 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0346 mL 10.1731 mL 20.3463 mL
5 mM 0.4069 mL 2.0346 mL 4.0693 mL
10 mM 0.2035 mL 1.0173 mL 2.0346 mL
50 mM 0.0407 mL 0.2035 mL 0.4069 mL


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