Description：

PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.

Chemical Information：

Molecular Weight (MW)		436.96
Formula		C20H25ClN4O3S
CAS No.		1373615-35-0
Solubility (25°C) *	DMSO	93 mg/mL (212.83 mM)
	Water	93 mg/mL (212.83 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2885 mL	11.4427 mL	22.8854 mL
5 mM	0.4577 mL	2.2885 mL	4.5771 mL
10 mM	0.2289 mL	1.1443 mL	2.2885 mL
50 mM	0.0458 mL	0.2289 mL	0.4577 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last