Description：

PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively.

Chemical Information：

Molecular Weight (MW)		479.92
Formula		C23H22ClN7O3
CAS No.		1402438-74-7
Solubility (25°C) *	DMSO	95 mg/mL (197.94 mM)
	Water	Insoluble
	Alcohol	1 mg/mL(2.08 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0837 mL	10.4184 mL	20.8368 mL
5 mM	0.4167 mL	2.0837 mL	4.1674 mL
10 mM	0.2084 mL	1.0418 mL	2.0837 mL
50 mM	0.0417 mL	0.2084 mL	0.4167 mL

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