Description：

PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.

Chemical Information：

Molecular Weight (MW)		474.48
Formula		C23H25F3N6O2
CAS No.		942487-16-3
Solubility (25°C) *	DMSO	0.4 mg/mL (0.84 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1076 mL	10.5379 mL	21.0757 mL
5 mM	0.4215 mL	2.1076 mL	4.2151 mL
10 mM	0.2108 mL	1.0538 mL	2.1076 mL
50 mM	0.0422 mL	0.2108 mL	0.4215 mL

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