Description：

PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.

Chemical Information：

Molecular Weight (MW)		665.66
Formula		C21H20F3N7O3S.C6H6O3S
CAS No.		939791-38-5
Solubility (25°C) *	DMSO	14 mg/mL warmed (21.03 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5023 mL	7.5113 mL	15.0227 mL
5 mM	0.3005 mL	1.5023 mL	3.0045 mL
10 mM	0.1502 mL	0.7511 mL	1.5023 mL
50 mM	0.0300 mL	0.1502 mL	0.3005 mL

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