Description：

AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.

Chemical Information：

Molecular Weight (MW)		347.38
Formula		C18H22FN3O3
CAS No.		836620-48-5
Solubility (25°C) *	DMSO	23 mg/mL (66.2 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

PDK1 12 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8787 mL	14.3935 mL	28.7869 mL
5 mM	0.5757 mL	2.8787 mL	5.7574 mL
10 mM	0.2879 mL	1.4393 mL	2.8787 mL
50 mM	0.0576 mL	0.2879 mL	0.5757 mL

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