Description：

Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with K_i of 1.3 nM, 7.2 nM and 65 nM, respectively.

Chemical Information：

Molecular Weight (MW)		516.42
Formula		C20H21N5O6.5/2H2O.2Na
CAS No.		357166-30-4
Solubility (25°C) *	DMSO	Insoluble
	Water	100 mg/mL warmed (193.64 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9364 mL	9.6820 mL	19.3641 mL
5 mM	0.3873 mL	1.9364 mL	3.8728 mL
10 mM	0.1936 mL	0.9682 mL	1.9364 mL
50 mM	0.0387 mL	0.1936 mL	0.3873 mL

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