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Description:
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2.
Chemical Information:
Molecular Weight (MW) 267.28 Formula
C16H13NO3
CAS No. 167869-21-8 Solubility (25°C) * DMSO 14 mg/mL warmed (52.37 mM) Water Insoluble Alcohol Insoluble
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Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.7414 mL 18.7070 mL 37.4139 mL 5 mM 0.7483 mL 3.7414 mL 7.4828 mL 10 mM 0.3741 mL 1.8707 mL 3.7414 mL 50 mM 0.0748 mL 0.3741 mL 0.7483 mL
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