Description：

PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.

Chemical Information：

Molecular Weight (MW)		561.09
Formula		C16H13BrF3IN2O4
CAS No.		391210-00-7
Solubility (25°C) *	DMSO	112 mg/mL (199.61 mM)
	Water	Insoluble
	Alcohol	14 mg/mL (24.95 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7822 mL	8.9112 mL	17.8225 mL
5 mM	0.3564 mL	1.7822 mL	3.5645 mL
10 mM	0.1782 mL	0.8911 mL	1.7822 mL
50 mM	0.0356 mL	0.1782 mL	0.3564 mL

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