Description：

PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Phase 2.

Chemical Information：

Molecular Weight (MW)		478.67
Formula		C17H14ClF2IN2O2
CAS No.		212631-79-3
Solubility (25°C) *	DMSO	96 mg/mL (200.55 mM)
	Water	Insoluble
	Alcohol	14 mg/mL (29.24 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0891 mL	10.4456 mL	20.8912 mL
5 mM	0.4178 mL	2.0891 mL	4.1782 mL
10 mM	0.2089 mL	1.0446 mL	2.0891 mL
50 mM	0.0418 mL	0.2089 mL	0.4178 mL

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