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Description:
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src.
Chemical Information:
Molecular Weight (MW) 523.67 Formula
C28H41N7O3
CAS No. 219580-11-7 Solubility (25°C) * DMSO 100 mg/mL (190.95 mM) Water Insoluble Alcohol 100 mg/mL (190.95 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9096 mL 9.5480 mL 19.0960 mL 5 mM 0.3819 mL 1.9096 mL 3.8192 mL 10 mM 0.1910 mL 0.9548 mL 1.9096 mL 50 mM 0.0382 mL 0.1910 mL 0.3819 mL
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