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Pazopanib HCl (GW786034 HCl)

Pazopanib HCl (GW786034 HCl)

Catalog Number: CC1191 Rank: comment rank 5

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Description:

Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.

Chemical Information:

Molecular Weight (MW) 473.98
Formula

 

C21H23N7O2S.HCl

 

CAS No. 635702-64-6
Solubility (25°C) * DMSO 17 mg/mL (35.86 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1098 mL 10.5490 mL 21.0979 mL
5 mM 0.4220 mL 2.1098 mL 4.2196 mL
10 mM 0.2110 mL 1.0549 mL 2.1098 mL
50 mM 0.0422 mL 0.2110 mL 0.4220 mL


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