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Description:
Palomid 529 (P529) inhibits both the mTORC1 and mTORC2 complexes, reduces phosphorylation of pAktS473, pGSK3βS9, and pS6 but no effect observed on pMAPK or pAktT308. Phase 1.
Chemical Information:
Molecular Weight (MW) 406.43 Formula
C24H22O6
CAS No. 914913-88-5 Solubility (25°C) * DMSO 81 mg/mL (199.29 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.4604 mL 12.3022 mL 24.6045 mL 5 mM 0.4921 mL 2.4604 mL 4.9209 mL 10 mM 0.2460 mL 1.2302 mL 2.4604 mL 50 mM 0.0492 mL 0.2460 mL 0.4921 mL
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