Description：

Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.

Chemical Information：

Molecular Weight (MW)		483.99
Formula		C24H29N7O2.HCl
CAS No.		827022-32-2
Solubility (25°C) *	DMSO	3 mg/mL warmed (6.19 mM)
	Water	30 mg/mL (61.98 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0662 mL	10.3308 mL	20.6616 mL
5 mM	0.4132 mL	2.0662 mL	4.1323 mL
10 mM	0.2066 mL	1.0331 mL	2.0662 mL
50 mM	0.0413 mL	0.2066 mL	0.4132 mL

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