Description：

OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.

Chemical Information：

Molecular Weight (MW)		443.44
Formula		C22H16F3N3O2S
CAS No.		728033-96-3
Solubility (25°C) *	DMSO	89 mg/mL (200.7 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (6.76 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2551 mL	11.2755 mL	22.5510 mL
5 mM	0.4510 mL	2.2551 mL	4.5102 mL
10 mM	0.2255 mL	1.1275 mL	2.2551 mL
50 mM	0.0451 mL	0.2255 mL	0.4510 mL

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