Description：

OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1.

Chemical Information：

Molecular Weight (MW)		406.44
Formula		C21H22N6O3
CAS No.		936890-98-1
Solubility (25°C) *	DMSO	18 mg/mL (44.28 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4604 mL	12.3019 mL	24.6039 mL
5 mM	0.4921 mL	2.4604 mL	4.9208 mL
10 mM	0.2460 mL	1.2302 mL	2.4604 mL
50 mM	0.0492 mL	0.2460 mL	0.4921 mL

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