Description：

Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with K_i of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Phase 1.

Chemical Information：

Molecular Weight (MW)		505.5
Formula		C25H17F2N5O3S
CAS No.		1086062-66-9
Solubility (25°C) *	DMSO	100 mg/mL (197.82 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9782 mL	9.8912 mL	19.7824 mL
5 mM	0.3956 mL	1.9782 mL	3.9565 mL
10 mM	0.1978 mL	0.9891 mL	1.9782 mL
50 mM	0.0396 mL	0.1978 mL	0.3956 mL

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