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Description:
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1.
Chemical Information:
Molecular Weight (MW) 434.46 Formula
C24H23FN4O3
CAS No. 763113-22-0 Solubility (25°C) * DMSO 86 mg/mL warmed (197.94 mM) Water 0.002 mg/mL (0.0 mM) Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3017 mL 11.5085 mL 23.0171 mL 5 mM 0.4603 mL 2.3017 mL 4.6034 mL 10 mM 0.2302 mL 1.1509 mL 2.3017 mL 50 mM 0.0460 mL 0.2302 mL 0.4603 mL
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