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Olaparib (AZD2281, Ku-0059436)

Olaparib (AZD2281, Ku-0059436)

Catalog Number: CC1216 Rank: comment rank 5

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Description:

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1.

Chemical Information:

Molecular Weight (MW) 434.46
Formula

 

C24H23FN4O3

 

CAS No. 763113-22-0
Solubility (25°C) * DMSO 86 mg/mL warmed (197.94 mM)
Water 0.002 mg/mL (0.0 mM)
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3017 mL 11.5085 mL 23.0171 mL
5 mM 0.4603 mL 2.3017 mL 4.6034 mL
10 mM 0.2302 mL 1.1509 mL 2.3017 mL
50 mM 0.0460 mL 0.2302 mL 0.4603 mL


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