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Odanacatib (MK-0822)

Odanacatib (MK-0822)

Catalog Number: CC1271 Rank: comment rank 5

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Description:

Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of cathepsin K (human/rabbit) with IC50 of 0.2 nM/1 nM, and demonstrated high selectivity versus off-target cathepsin B, L, S. Phase 3.

Chemical Information:

Molecular Weight (MW) 525.56
Formula

 

C25H27F4N3O3S

 

CAS No. 603139-19-1
Solubility (25°C) * DMSO 100 mg/mL (190.27 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9027 mL 9.5137 mL 19.0273 mL
5 mM 0.3805 mL 1.9027 mL 3.8055 mL
10 mM 0.1903 mL 0.9514 mL 1.9027 mL
50 mM 0.0381 mL 0.1903 mL 0.3805 mL


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