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NVP-CGM097

NVP-CGM097

Catalog Number: CC8031 Rank: comment rank 5

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Description:

NVP-CGM097 is a highly potent and selective MDM2 inhibitor. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway.

Chemical Information:

Molecular Weight (MW) 659.26
Formula

 

C38H47ClN4O4

 

CAS No. 1313363-54-0
Solubility (25°C) * DMSO 65 mg/mL (98.59 mM)
Water Insoluble
Alcohol 65 mg/mL (98.59 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.5169 mL 7.5843 mL 15.1685 mL
5 mM 0.3034 mL 1.5169 mL 3.0337 mL
10 mM 0.1517 mL 0.7584 mL 1.5169 mL
50 mM 0.0303 mL 0.1517 mL 0.3034 mL


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