Description：

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.

Chemical Information：

Molecular Weight (MW)		453.58
Formula		C28H31N5O
CAS No.		475488-23-4
Solubility (25°C) *	DMSO	10 mg/mL warmed (22.04 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (6.61 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2047 mL	11.0234 mL	22.0468 mL
5 mM	0.4409 mL	2.2047 mL	4.4094 mL
10 mM	0.2205 mL	1.1023 mL	2.2047 mL
50 mM	0.0441 mL	0.2205 mL	0.4409 mL

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