Description：

NT157, a selective inhibitor of IRS-1/2(insulin receptor substrate), has the potential to inhibit IGF-1R and STAT3 signaling pathways in cancer cells and stroma cells of TME leading to a decrease in cancer cell survival.

Chemical Information：

Molecular Weight (MW)		412.26
Formula		C16H14BrNO5S
CAS No.		1384426-12-3
Solubility (25°C) *	DMSO	82 mg/mL (198.9 mM)
	Water	Insoluble
	Alcohol	82 mg/mL (198.9 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4257 mL	12.1283 mL	24.2565 mL
5 mM	0.4851 mL	2.4257 mL	4.8513 mL
10 mM	0.2426 mL	1.2128 mL	2.4257 mL
50 mM	0.0485 mL	0.2426 mL	0.4851 mL

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