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Description:
NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA.
Chemical Information:
Molecular Weight (MW) 530.96 Formula
C24H35N7.3HCl
CAS No. 1177865-17-6 Solubility (25°C) * DMSO 100 mg/mL warmed (188.33 mM) Water 100 mg/mL warmed (188.33 mM) Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.8834 mL 9.4169 mL 18.8338 mL 5 mM 0.3767 mL 1.8834 mL 3.7668 mL 10 mM 0.1883 mL 0.9417 mL 1.8834 mL 50 mM 0.0377 mL 0.1883 mL 0.3767 mL
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